An examination of TOR1A variants in recurrent major depression

[摘要] BackgroundObservations of comorbid depression in subjects with primary dystonia have suggested a dual role for the TOR1A gene in mood disorders and movement disorders. We conducted a systematic search for carriers of the ΔGAG deletion and for other variants in TOR1A exon 5 among 414 Caucasian subjects with recurrent major depression from the Upper Palatinate.

[学科分类] 流行病学

[关键词] DYT1;TOR1A;torsion dystonia;recurrent major depression;genetic variation