Applications of Fourier Domain Mode Locked lasers for optical coherence tomography imaging

[摘要] (cont.) Working in collaboration with industrial partners, a 3D-OCT imaging system incorporating an FDML laser is constructed for clinical research in gastroenterology. Spiral-scanning imaging catheters are developed for use in the human esophagus and colon, enabling high-density 3D-OCT endomicroscopy of the gastrointestinal tract. Finally, clinical pilot studies are conducted in collaboration with medical partners to demonstrate the utility of 3D-OCT endomicroscopy for pathology detection, treatment planning, and follow-up assessment. The convergence of 3D spatial resolution, imaging speed, field of view, and minimally invasive access enabled by 3D-OCT are unmatched by most other biomedical imaging techniques. Though still early on in its development, 3D-OCT may have a profound impact on human healthcare and industrial inspection by enabling visualization and quantification of 3D sample microstructure in situ and in real time.

[发布机构] Massachusetts Institute of Technology