Differentiation therapy: a promising strategy for cancer treatment

[摘要] Poor differentiation is an important hallmark of cancer cells, and differentiation therapy holds great promise for cancer treatment. The restoration of IkB kinase α (IKKα) leads to the differentiation of nasopharyngeal carcinoma cells with reduced tumorigenicity. The findings by Yan et al. validate the polycomb protein enhancer of zeste homologue 2 (EZH2) as a target for intervention.

[学科分类] 肿瘤学

[关键词] Differentiation therapy;Cancer treatment;IkB kinase α