Assembly and post-assembly manipulation of polyelectrolyte multilayers for control of bacterial attachment and viability

[摘要] (cont.) At high pH values, PAH adsorbed onto the surface with many unbound uncharged amine groups. When the multilayer was exposed to physiological pH values for bacteria assays, the amine groups became protonated and participated in a cationic-killing effect. Finally, biofilm control was examined by investigating initial biofilm formation on films of various mechanical stiffness and surface charge. No differences were visible via optical microscopy. An alternative approach to biofilm control was considered whereby a dissociating multilayer region lifted-off a contaminated layer, exposing a clean, unfouled underlying surface.

[发布机构] Massachusetts Institute of Technology