TUMOR DIAGNOSIS AND PROGNOSIS

[摘要] It has been found that the level of protein tyrosine phosphatase ;;alpha;; (PTP;;alpha;;) expression is increased in significant numbers of tumors and that PTP;;alpha;; can be used as a marker for the diagnosis or prognosis of cancers. Accordingly, the invention provides a method for diagnosis or prognosis of a cancer, which method comprises detection of PTP;;alpha;; or PTP;;alpha;; nucleic acid. In general, the level of PTP;;alpha;; or PTP;;alpha;; nucleic acid in a first biological sample derived from tissue suspected of being neoplastic or potentially neoplastic is compared with the level in a second biological sample derived from normal tissue.