Circulating Prolidase Activity in Patients with Myocardial Infarction

[摘要] BackgroundCollagen is a major determinant of atherosclerotic plaque stability. Thus, identification of differences in enzymes that regulate collagen integrity could be useful for predicting susceptibility to atherothrombosis or for diagnosing plaque rupture. In this study, we sought to determine whether prolidase, the rate-limiting enzyme of collagen turnover, differs in human subjects with acute myocardial infarction (MI) versus those with stable coronary artery disease (CAD).

[学科分类] 心脏病和心血管学

[关键词] prolidase;atherothrombosis;acute myocardial infarction;diabetes;coronary artery disease