Short- and Long-Term Renal Outcome of Hemolytic-Uremic Syndrome in Childhood

[摘要] Introduction: Hemolytic-uremic syndrome (HUS) is a common cause for intrarenal acute kidney injury in childhood. More than 90% of HUS cases are associated with an infection by Shigatoxin-producing Escherichia coli (STEC) whereas the reminder comprises a heterogeneous group (here classified as Non-STEC-HUS). Renal impairment can persist in patients with HUS. This study presents data from four decades investigating the short- and long-term outcome of HUS in childhood.

[学科分类] 儿科学

[关键词] hemolytic uremic syndrome;children;renal sequelae;EHEC;Shigatoxin