Clinical and Pathological Correlation in Pediatric Invasive Pulmonary Aspergillosis

[摘要] IntroductionInvasive’ pulmonary aspergillosis (IPA) has been one of the major causes of mortality in immunocompromised patients. The gold standard method for a diagnosis of IPA is histopathological examination of the lung tissue; however, post-procedural bleeding limits the feasibility of lung biopsy. The European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and The National Institute of Allergy and Infectious Disease Mycoses Study Group (EORTC/MSG) defined IPA. The objective of this study was to validate the EORTC/MSG 2008 definition of IPA, compared with histopathology in the pediatric population.

[学科分类] 儿科学

[关键词] invasive pulmonary aspergillosis;pediatric;histopathology;definition;sensitivity