Autoimmune Gastritis in the Pediatric Age: An Underestimated Condition Report of Two Cases and Review

[摘要] Background: Diagnosis of pediatric autoimmune gastritis (AIG) in children is important due to poor outcome and risk of malignancy. This condition is often underestimated in the clinico-pathologic diagnostic work-up, leading to delayed time-to-diagnosis. To increase the awareness of this condition in the pediatric population, we present two cases encountered at our institution, discuss their clinical, biological, and histological presentations in relation with evidence from the literature, and propose an algorithm for diagnosis and follow-up of AIG in children.

[学科分类] 儿科学

[关键词] autoimmune gastritis;gastric atrophy;children;intestinal metaplasia;ECL cell hyperplasia;iron-deficiency anemia