Comparison of antibacterial activity inhibitory of black cumin (Nigella sativa) oil, Cresophene®, and Calcium hydroxide

[摘要] ABSTRACTIntroduction:Black cumin(Nigella sativa)oil is a natural antibacterial product containing thymoquinone.Thymoquinoneis a powerful antibacterial substance towards gram-positive bacteria. The research objective was to compare the inhibitory effects of black cumin oil, Cresophene® and Ca(OH) 2towards the growth ofStaphylococcus aureus. Methods:Experimental laboratory by takingStaphylococcus aureusfrom deciduous teeth pulp necrosis that has been isolated in Brain-Heart Infusion (BHI) medium. Inhibitory of black cumin oil, Cresophene® and Ca(OH) 2were measured by making three different 6 mm diameter wells contained each substances. Data then analyzed by two-way ANOVA using statistical analysis program.Results:Cresophene® had the largest inhibitory zone with the average zone was 32 ± 0.05mm and stable from the 1 stday until the 4 thday then decreased on the 5 thday and remain stable until the 7 thday. Ca(OH) 2had average inhibitory zone of 15.9 ± 0:10 mm and remain stable from the 1 stday until the 7 thday. Black cumin oil had average inhibitory zone of ± 7.9 ± 0.2 mm and remain stable from the 1 stday until the 7 thday.Conclusion:The inhibitory zone towardsStaphylococcus aureusisolated from deciduous teeth pulp necrosis consecutively was Cresophene®, Ca(OH) 2and black cumin oil. Keywords :Staphylococus aureus,Black cumin oil, Cresophene® ,Ca(OH) 2 , Inhibitory zone .

[学科分类] 口腔科学

[关键词] Staphylococus aureus;Black cumin oil;Cresophene®;Ca(OH)2;Inhibitory zone