Antibacterial activity of Zingiber officinale roscoe extract as a potential root canal irrigation solution against Enterococcus faecalis

[摘要] Introduction:This study was aimed to determine and formulate antibacterial activity ofZingiber Officinale Roscoe( Z. officinale ) extract againstEnterococcus faecalis (E. faecalis)as a potential irrigating solution which is easily available and cost-effective.Methods: Extract ofZ. officinale Roscoewas yielded through soxhlet technique. Samples divided into two groups, i.e., the extract ofZ. officinaleRoscoe and chlorhexidine 2% as a control. The antimicrobial activity was observed using the diffuse agar method. Minimum inhibitory concentration (MIC) was determined by serial microdilution method, and minimum bactericidal concentration (MBC) was determined by cultured samples in blood agar. Data were analysed using ANOVA and Kruskal-Wallis test.Results : Extract ofZingiber officinaleRoscoe has antimicrobial activity againstE. faecaliswith the MBC of 15.625 mg/mL. (p<0,05).Conclusion:Extract ofZingiber officinaleRoscoe have shown antibacterial activity against  E. faecalisand can be further developed as a potential root canal irrigation solution.

[学科分类] 口腔科学

[关键词] Antibacterial activity;Enterococcus faecalis;extract of Zingiber officinale Roscoe;root canal irrigating solution.