经PICC与外周静脉输注奥沙利铂的神经毒性反应观察及护理

[摘要] Abstract：Objective To observe the oxaliplatin neurotoxicity via peripherally inserted central catheters(PICC)and peripheral intravenous, and to summarize peripheral intravenous infusion and related nursing measures. Methods Totally 100 patients with digestive system cancer undergoing oxaliplatin chemotherapy were assigned to the study group(n=50)and the control group(n=50). Patients in the study group received oxaliplatin infusion via PICC while those in the control group received oxaliplatin infusion via peripheral intravenous. The oxaliplatin neurotoxicity during chemotherapy was observed and compared between two groups. Results Patients in the study group has less severity of oxaliplatin neurotoxicity compared with those in the control group(P<0.05). Conclusion Infusion via PICC can reduce the severity of oxaliplatin neurotoxicity. Targeted nursing measures are necessary to improve the patients ‘quality of life during chemotherapy.

[学科分类] 护理学

[关键词] 经外周静脉置入的中心静脉导管;外周静脉;奥沙利铂;神经毒性;针对性护理