个体化综合心理干预对造血干细胞移植期间患者负性情绪及营养状况的影响

[摘要] Abstract：Objective To explore the effect of individualized comprehensive psychological intervention on negative emotion and nutritional status in patients undergoing hematopoietic stem cell transplantation(HSCT).  Methods A total of 60 patients with HSCT were randomly assigned to 2 groups. Thirty patients in the control group received routine nursing care, while 30 patients in the intervention group received individualized comprehensive psychological intervention in addition to routine nursing care. The negative mood were evaluated by selfrating anxiety scale (SAS) and selfrating depression scale (SDS) in both groups before and at 4 weeks after HSCT. The nutritional indexes were measured and the nutritional status was evaluated by subjective global assessment (SGA). Results The scores of SAS and SDS in the intervention group were significantly lower than those in the control group at 4 weeks after HSCT(P＜0.05). The nutritional indexes at 4 weeks after HSCT were significantly declined than those before HSCT in both groups(P＜0.05 or P＜0.01). At 4 weeks after HSCT, the body mass index, triceps skinfold, arm circumference and plasma prealbumin in the intervention group were significantly better than those in the control group(P＜0.05). The incidence of malnutrition in the intervention group was significantly lower than that in the control group(P＜0.05). Conclusions The individualized comprehensive psychological intervention could help to improve patients with negative emotion and reduce the extent of decreased nutritional status and the incidence of malnutrition in patients undergoing HSCT.

[学科分类] 护理学

[关键词] 造血干细胞移植;负性情绪;营养状况;心理干预