右美托咪定在重型颅脑损伤患者中的应用及护理

[摘要] Abstract：Objective To analyze the application efficacy of dexmedetomidine in the patients with severe craniocerebral injury, and to summarize corresponding nursing measures. Methods The clinical data of 63 patients with severe craniocerebral injury who received dexmedetomidine for sedation and analgesia were retrospectively analyzed. The condition of respiration, heart rate, blood pressure and acroteric oxygen saturation fluctuation of patients were observed during application of dexmedetomidine. Results 〓After application of dexmedetomidine, the restlessness got better. A small dose of midazolam or propofol was combined for the patients with invasive respirator if necessary, there was no obvious man-machine counteraction, and the heart rate and blood pressure fluctuation became stable compared with pre-sedation. The heart rate of 7 out of 63 patients decreased less than 60 times per minute, but got better after reduced administration speed. All the patients didn't suffer from respiratory depression obviously. Conclusion 〓Moderate dose of dexmedetomidine in patients with severe craniocerebral injury for sedation and analgesia can reduce the restlessness, decrease intracranial pressure and cerebral metabolic rate of oxygen, inhibit sympathetic storm, and improve prognosis and quality of life in combination of corresponding nursing measures.

[学科分类] 护理学

[关键词] 右美托咪定;重型颅脑损伤;镇静;镇痛;护理对策