Cyclopropanation of dienol ethers

[摘要] The copper-catalysed, thermal decompositions of ethyl diazoacetate and diazoacetone in the presence of 1-methoxycyclohexa-1,3-diene, l-methoxy-4-methylcyclohexa-l,3-diene, 1-methoxybuta-l,3-diene, 1-ethoxybuta-l,3-diene and 1-trimethylsilyloxybuta-1,3-diene and the acid hydrolysis of the resultant cyclopropanes are described. These reactions constitute a simple, two-step procedure for the production of olefinic 1,4- and 1,6-dicarbonyl compounds, starting from dienol ethers of a,g -unsaturated aldehydes and ketones.

[发布机构] Rice University