Genetic variants and phylogenetic analysis of Haemophilusparasuis (HPS) OMPP2 detected in Sichuan, China from 2013 to2015

[摘要] To investigate the genetic variation in Haemophilus parasuis (HPS) inSichuan, China, 11 isolates were analyzed based on the outer membrane protein P2(OMPP2) sequence. Sequence analysis showed that the 11 isolates shared93.0 to 100% nucleotide homology with 15 reference strains, and the consistency betweenthe 26 strains was 89.0%. The isolates of HPS-1, 2, 4, 5, 6, 7, 8, 10 and 11 had a 69-basedeletion from 770 base pairs (bp) to 850 bp, which was infrequent in China. Thephylogenetic tree showed that HPS-3 and HPS-8 had closer relationships with European andJapanese strains, but shared 98.7% nucleotide homology with the SW114 Japanese strain.

[学科分类] 兽医学

[关键词] haemophilus parasuis;outer membrane protein;sequence analysis