Lissencephaly in a Pekingese

[摘要] A 1-year-old neutered male Pekingese was presented for evaluation and further treatmentof cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion wassuspected following neurological examination. The dog showed signs of learning difficulty.Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex witha reduced number of gyri, as well as a cystic lesion associated with the quadrigeminalcistern. A diagnosis of lissencephaly, concurrent with a quadrigeminal cisternal cyst, wasmade. High-dose and multiple anticonvulsants were necessary to control the seizures. Thisis the first report of lissencephaly in a Pekingese.

[学科分类] 兽医学

[关键词] lissencephaly;magnetic resonance imaging;Pekingese