Isolation of equine papillomavirus type 1 from racing horse inJapan

[摘要] Although many studies have been conducted worldwide for Equus caballus papillomavirus(EcPV), limited information is available on the virus in Japan. We recently collected oneclassical viral papillomatosis sample (E150904) from a racing horse in Japan.Papillomavirus infection was confirmed by histopathology, immunohistochemistry and PCRassays, and the sample was diagnosed as epithelial papilloma. Full-length genome of thevirus was cloned and sequenced. It was 7,613 bp in length and had the same genomeorganization with reported EcPV-1. Moreover, phylogenetic analysis based on L1 generevealed that the infection was caused by a variant of EcPV-1. This is the first report ofEcPV infection in Japan, and would further contribute to the molecular epidemiological andpathological studies for EcPV.

[学科分类] 兽医学

[关键词] EcPV type 1;equine papillomatosis;initial detection;racing horse