Concurrent with T-zone lymphoma and high-grade gastrointestinal cytotoxicT-cell lymphoma in a dog

[摘要] A 9-year-old, spayed female Golden Retriever dog was referred to us for lymphocytosis andlymphadenopathy, secondary to suspected chronic lymphocytic leukemia (CLL). The dog had aclinical history of anorexia, vomiting and melena lasting two days. The popliteal lymphnode contained small-to-intermediate lymphocytes, which led us to suspect low-gradelymphoma. Thickened lesions in the stomach and small intestine were detected byultrasonography. Histopathology of the popliteal lymph node and small intestine revealed asimultaneous presence of T-zone lymphoma (TZL) and high-grade gastrointestinal (GI)cytotoxic T-cell lymphoma. Large granular lymphocytes (LGLs) were seen on cytologicalexamination. Polymerase chain reaction (PCR) revealed that both lymphomas originated inthe T-cells. The dog died 15 days after diagnosis, despite chemotherapy.

[学科分类] 兽医学

[关键词] canine;gastrointestinal lymphoma;large granular lymphocytic lymphoma;PARR;T-zone lymphoma