Isolation and molecular characterization of parainfluenza virus 5 indiarrhea-affected piglets in China

[摘要] Recently, parainfluenza virus 5 (PIV5) infection has been increasingly reported inmammals. In this study, five PIV5 strains were isolated from diarrhea-affected pigletsfrom four provinces or municipalities in China. An F-gene-based phylogenetic treeindicated that the five isolated strains were closely related to the PIV5 strain ZJQ-221from a lesser panda in China, and the PIV5 strain 1168-1 from a dog in South Korea. Thenew isolates differed genetically from other pig, calf, rhesus macaque kidney cells,human, and dog PIV5 reference strains. Our study reveals the presence of PIV5 inintestinal tissue samples collected from diarrhea-affected piglets, and provides novelinformation regarding the epidemiology and tissue tropism of PIV5.

[学科分类] 兽医学

[关键词] diarrhea-affected piglet;isolation;parainfluenza virus 5