Intermediate-grade mammary gland adenocarcinoma in an 18-year-old femaleblack leopard (Panthera pardus) with acute pancreatic necrosis andchronic interstitial nephropathy

[摘要] An 18-year-old female black leopard (Panthera pardus) showed renalfailure, leukocytosis and presence of subcutaneous masses in the lower abdominal regionand right shoulder; she eventually died. Histopathological observations included a mammarygland carcinoma with comedo, solid and tubulopapillary patterns in subcutaneous tissue,and highly proliferated tumor cells in systemic organs. The tumor cells were positive forcytokeratin AE1/AE3. The mammary gland tumor was diagnosed as intermediate-gradeadenocarcinoma, based on a previously reported histological grading system of felinemammary carcinomas. Chronic interstitial nephritis was estimated to have been ongoing for5 years, whilst acute necrotic pancreatitis in relation to tumor metastasis could havebeen the cause of death.

[学科分类] 兽医学

[关键词] mammary gland tumor;nephritis;nondomestic zoo fields;pancreatitis