PD-L1 expression in squamous-cell carcinoma and adenocarcinoma of the lung

[摘要] BackgroundWith introduction of immunotherapy (IT) into the treatment of advanced non-small-cell lung cancer (NSCLC), a need for predictive biomarker became apparent. Programmed death ligand 1 (PD-L1) protein expression is most widely explored predictive marker for response to IT. We assessed PD-L1 expression in tumor cells (TC) and immune cells (IC) of squamous-cell carcinoma (SCC) and adenocarcinoma (AC) patients.

[学科分类] 肿瘤学

[关键词] lung cancer;squamous-cell lung cancer;adenocarcinoma;tumor cells;immune cells;PD-L1 expression