Premalignant gastric lesions in patients included in National colorectal cancer screening

[摘要] BackgroundGastric cancer is the fifth most common malignancy in the world with almost one million new cases annually. Helicobacter pylori infection causes 89% of all gastric cancers. Premalignant lesions (atrophy and intestinal metaplasia) develop after several decades of inflammation. Secondary prevention with gastroscopy is possible, but it is costly and has a low compliance rate. Alternative procedures like serology testing for pepsinogen I and II and pepsinogen I/II ratio are available to select patients for surveillance gastroscopies.

[学科分类] 肿瘤学

[关键词] gastropanel;Helicobacer pylori;atrophy;intestinal metaplasia;gastric cancer