Update on Prevention and Treatment of Surgical Blood Loss

[摘要] Surgical bloodloss is one of the biggest challenges facing surgeons today. The demand forhighly complex surgeries has increased for multiple reasons. A review was madeof the main factors that influence blood loss at each stage of surgery, withemphasis on orthopedic surgical procedures. Existing hemostatic drugs that helpprevent such loss and avoid the risk of transfusion were examined and evaluated.Various factors such as anemia, advanced age, the existence of comorbidities,prolonged surgical time, the use in the postoperative of medicines in orderto achieve anticoagulation, favor surgical blood loss and elevate blood transfusionrates. The use of hemostatic agents should be based on the clinical sense ofthe expected therapeutic efficacy, safety against possible complications andthe economic costs of its administration.

[学科分类] 生理学

[关键词] loss of blood;haemostatic agents;risk of transfusion.