Synthesis and characterization of gelatin based polyester urethane scaffold

[摘要] For tissue engineering purpose two gelatin based polyester urethane scaffolds of different compositions were prepared from lactic acid, polyethylene glycol 400 (PEG 400) and characterized by FTIR, XRD for their mechanical and morphological properties using SEM and optical microscopic analyses. Degradation and swelling studies of gelatin based polyester urethane scaffolds in phosphate buffer saline (PBS) were performed. Human keratinocyte cells were cultured within these scaffolds, which showed good cell adherence and proliferation.

[学科分类] 材料工程

[关键词] Polyester urethane;scaffold;tensile strength;swelling;degradation;cell culture.