Mechanical properties of F-actin network

[摘要] (cont.) Measurement of mechanical properties as a function of external strain demonstrated that some regions exhibited strain-hardening while the others showed strain-softening. Aligned stretching of actin filaments observed at high strain seemed to play a role in strain-stiffening. By comparing the behaviors of an F-actin network cross-linked with wildtype and mutant FLNa, it was demonstrated how molecular structure of the ABP alters the mechanical behavior of F-actin network.

[发布机构] Massachusetts Institute of Technology