Secondary pulmonary alveolar proteinosis after lung transplantation: axc2xa0single-centre series

[摘要] ExtractPulmonary alveolar proteinosis (PAP) is a rare disease characterized by accumulation of surfactant in alveolar space related to alveolar macrophage dysfunction. PAP occurs in three clinically distinct forms: autoimmune PAP (90% of cases); secondary PAP and genetic PAP [1]. Secondary PAP may be related to immunosuppressive disorders; with few cases associated with solid-organ transplant [1]. Indeed; to our knowledge; only five cases of symptomatic PAP secondary to lung transplantation have been reported [2xe2x80x934].

[学科分类] 呼吸医学