GOLD 2017 on the way to a phenotypic approach? Analysis from the Phenotypes of COPD in Central and Eastern Europe (POPE) Cohort

[摘要] ExtractRecently; the Global Initiative for Chronic Obstructive Lung Disease (GOLD) released a revised consensus report (2017 GOLD Report) [1] in which the formerly defined ABCD classification of patients with COPD has been refined. The 2011 GOLD Report and its 2016 Update classified patients on the basis of three variables; i.e. the symptom burden; lung function impairment and exacerbations [2]; now the Axe2x80x93D groups are defined solely on the basis of symptoms and history of exacerbations xe2x80x93 thus recognising the limitations of the forced expiratory volume in 1 s (FEV1) in influencing therapeutic decisions in COPD [1]. The obvious consequence of the new classification is a shift of a proportion of patients from the C to the A group; and from the D to the B group. Nevertheless; the magnitude of such redistribution remains unknown.

[学科分类] 呼吸医学