The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase

[摘要] For a successful pregnancy to occur, foreign genetic material such as the allogeneic fetus must be tolerated within the maternal host.Indoleamine 2,3-dioxygenase (IDO) is an enzyme induced by pro-inflammatory cytokines that has been shown to be key to this process.Obesity as a pro-inflammatory state is associated with poor obstetric outcomes.The primary objective of this study is to investigate the relationship between obesity and IDO activity.

[学科分类] 妇产科学

[关键词] Preeclampsia;obesity in pregnancy;immunology of pregnancy;fetal tolerance