A Retrospective Case Review of Soft Tissue Oral Malignancies & Associated Clinicopathologic Features (1991-2016)

[摘要] Intraoral soft tissue masses can clinically present as benign, premalignant, or malignant lesions. Variability in presentation of soft tissue masses bear the possibility of misdiagnosis not only by general dentists but also by specialists. After a differential diagnosis is formulated, histopathologic evaluation is essential for establishing a definitive diagnosis.Neoplastic oral lesions in their early stages are subtle, which can make diagnosis challenging.Dentists play a vital role in the prevention of oral malignancy by early detection, and a thorough understanding of the diagnostic features. However, as most intraoral pathology is benign, clinicians frequently do not include malignancy in their differential diagnosis for soft tissue masses.1 The aim of this study is to emphasize the need of for histologic diagnosis of seemingly benign soft oral lesions as the clinical impression may not be accurate.2-6It is hypothesized that there will be a large number (~5%) of false negative diagnoses. Cases in which the clinical diagnosis is a benign entity (e.g. fibroma or pyogenic granuloma) but, upon histologic confirmation the pathologic diagnosis of a malignant soft tissue mass. We will also identify which clinical features (i.e. size, color, or clinical differential diagnoses) were most commonly diagnostic pitfalls. The purpose of the study is to elucidate the features most commonly associated with malignancy.

[发布机构] the University of Pittsburgh