PREVALENCE OF Rh AND ABO BLOOD GROUPS IN HIV SEROPOSITIVE PREGNANT WOMEN IN ENUGU, NIGERIA

[摘要] HIV status and blood groups determination (Rhesus and ABO groups) in 3691 pregnant women attending antenatal clinic at a Mission Hospital and Maternity and 1199 non-pregnant women visiting the same institution for marriage-related matters, or blood donation, or out-patient department between 1999 - 2002 were studied. Blood sample from each subject was screened for HIV using the quick test kits and tested for blood group types with anti-sera A,B,AB, and D. Overall, the prevalence of bloodgroup O+ was higher than in the general population with highest rate of 62.9% in HIV+ pregnant women followed by 58.4% in HIV- pregnant women and 58.0% in non-pregnant women. No difference was observed in groups A+, B+, AB+, O- for the three categories of subjects studied. Blood groups B-, AB- were conspicuously absent in HIV+ pregnant women but non-significant in HIV- pregnant women and the control. A- was very few in all the categories. Rh -ve accounted for 3.16%( HIV+), 3.46%( HIV-) and 2.67%( Control) while Rh +ve were 96.84%( HIV+), 96.06% ( HIV-) and 97.33%( Control). Thus, the higher than normalprevalence of group O+ in HIV+ pregnant women is indicative of the population size for this group. The very low prevalence ofRh -ve in type A-suggests that incompatibility could be higher than in this population and protective in HIV infection contraryto the previous report in apparently healthy population. The obvious absence of Rh- in AB group suggests that AB may have a higher percentage of protection against immunization. Hence in group B, less incidence of Rh incompatibility and haemolytic disease of the young in the mothers in blood group AB will occur.

[学科分类] 内科医学

[关键词] Rhesus genes, ABO blood groups, prevalence, Pregnant women, HIV seropositive.