Molecular genetic changes in benigncolorectal tumors synchronous with microsatelliteunstable carcinomas do not support a field defect

[摘要] Background: A colorectal cancer may develop through a particular molecular genetic pathway； raising the question of whether the particular molecular changes are random； or are unique to the particular segment of colon. We wanted to determine whether molec

[学科分类] 流行病学

[关键词] Adenoma； BRAF gene； colorectal cancer； field defect； hyperplastic polyp； KRAS gene； methylation； microsatellite instability； sessile polyp