DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation
[摘要] Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair genes and its overexpression contr
[发布日期] [发布机构]
[效力级别] [学科分类] 肿瘤学
[关键词] Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase;is clearly related to abnormal methylation of tumour suppressor genes;DNA repair genes and its overexpression contrib [时效性]
