Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells

[摘要] Cisplatin is a common chemotherapeutic drug for cancer treatment； but its effect is limited because of its cytotoxicity and chemoresistance. The combinational use of cisplatin with some natural compounds has provided a potential option to improve its effe

[学科分类] 肿瘤学

[关键词] Cisplatin； melatonin； hepatocellular carcinoma； NF-κB； AP-2β； COX-2； hTERT