No Evidence of Rat Hepatitis E Virus Excretion in Urine Samples of Rats

[摘要] To investigate whether rat hepatitis E virus (rat HEV) is excreted in the urine of HEV-infected rats, we infected 3 Wistar and 6 nude rats with rat HEV and examined the rat-HEV RNA in serum, fecal, and urine samples. We detected rat-HEV RNA in the serum and fecal samples of all 9 rats but not in any of the urine samples. Our results suggest that in rats, rat HEV is not transmitted via urine.

[学科分类] 传染病学

[关键词] hepatitis E virus;rat HEV;rat;urine