MICROSTELLITES: SIMPLE SEQUENCES WITH DYNAMIC ROLE IN FISH GENETICS

[摘要] Microsatellite or short tandem repeats (STRs) represent codominant molecular genetic markers and are scattered ubiquitously distributed within genomes of all prokaryotic and eukaryotic organisms. Being highly polymorphic and relatively small, these markers are extensively used in an array of fundamental and applied fields of life and medical sciences. Rapid exploitation of microsatellite loci has provided biologists with a set of molecular tools with unsurpassed versatility. In the field of aquaculture, microsatellites are proven tools for the characterization of genetic stocks, broodstock selection, constructing dense linkage maps, mapping economically important quantitative traits, identifying genes responsible for these traits and application to marker-assisted breeding programmes. In this review, functional and practical applications of microsatellites are considered, with special emphasis on fish genetics and aquaculture.

[学科分类] 基础医学

[关键词] Microsatellites;fisheries;Genetic diversity;Conservation Genetics;genetic mapping