COMPARATIVE STUDY OF IN VITRO FREE RADICAL SCAVENGING ACTIVITY OF DIFFERENT LEAF EXTRACTS OF IXORA COCCINEA L.

[摘要] In this study free radical scavenging activity of chloroform, methanolic and aqueous leaf extracts of Ixora coccinea L. (Rubiaceae) were determined and compared by in vitro assay models such as DPPH free radical, nitric oxide radical, hydroxyl radical scavenging assay, reductive ability and total antioxidant capacity. Ascorbic acid was used as reference standard. IC50 of all the exracts in all the method were determined. Among all the three extracts, methanolic extract have shown better scavenging and antioxidant property compared to other extracts in all the assay methods evaluated thereby leading it into the modern system of medicine in future.

[学科分类] 基础医学

[关键词] Free radical;Antioxidant;Ixora coccinea;DPPH