Analytical study of effects of intravenous lignocaine on pressor response during laryngoscopy and intubation

[摘要] Induction of general anaesthesia and endotracheal intubation for maintenance of airway and prevention of aspiration is carried out frequently by the anaesthesiologist in day to day practice. This study was aimed to study the effects of Magnesium suplhate on pressor response during laryngoscopy and intubation. It was carried out in 50 patients of both sexes, between the age group of 20-60 years, belonging to ASA physical status grade I and II. 2% preservative free lignocaine 1.5mgKg-1 diluted to 10ml over a period of one minute given intravenously before inbutation resulted in tachycardia after intubation. But at the end of 5 minutes, the heart rate was still higher in lignocaine group. We found out that intravenous lignocaine is less effective to attenuate the pressor response and a better alternative should be used after further comparative studies.

[学科分类] 基础医学

[关键词] Anesthesiology