The Effects of Transcranial Direct Current Stimulation (TDCS) on Reducing the Desire for Methadone among Addicts under Treatment in Taleghani Hospital of Ilam, Iran 2016

[摘要] Introduction: At the moment, abusing illicit drugs and addiction is considered as one of great challenges all over the world. The desire stage in the addiction cycle is assumed to be a key element in abuse relapse. The main objective of the current study is to investigate the effects of tDCS (Transcranial Direct Current Stimulation) on addicts under treatment in Taleghani Hospital of Ilam 2016. Martials and Methods: The current study is a semi-experimental study. 40 people are divided into two groups, an experimental group of 20 individuals and a control group of 20 participants in order to investigate them. The experimental group will go through 20 sessions of Frontal 3 Anodal electrode stimulus and cathodal right shoulder electrode stimulus with a 48-hour distance between the sessions. Moreover, the control group will go through afictional transcranial electric stimulus on the skull. In order to analyze the obtained data, SPSS software application version 16 is used. Results: The results of the study show that the highest frequency is seen among people under 35 years of age and the most common used illicit substance is opium. Moreover, assessing the induced desire in pre-test and post-test groups indicates that the highest average difference is related to the effects of tDCS in Anodal Frontal 3 stimulus. (P=0.0001) Conclusion: The results show that Anodal Frontal 3 stimulus will reduce methadone craving significantly compared to cathodal right shoulder stimulus. It is recommended that the tDCS method be used as a complementary treatment method for reducing drug cravings.

[学科分类] 药理学

[关键词] Reza Valizadeh;Masoumeh Otaghi;Farzaneh Kaki;Foruzan Kavarizadeh;Transcranial Direct Current Stimulation (tDCS);Methadone Addicts;Iran;Ilam.