Anti-Candida Effect of Allium Sativum

[摘要] Introduction: Allium Sativum, commonly known as garlic, is a bulbous plant with hermaphrodite flowers, a species in the onion genus, Allium , native to central Asia.The objective of this study was to review Anti-Candida specie effect of Allium Sativum. Methods: This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. The initial search strategy identified about 98 references. In this study, 49 studies was accepted for further screening and met all our inclusion criteria [in English, full text, therapeutic effects of Allium Sativum and dated mainly from the year 1992 to 2016.The search terms were “Allium Sativum”, “therapeutic properties”, “pharmacological effects". Result: the antimicrobial efficacy of AGE to be dose and time dependent, producing five distinct time-kill profiles among the isolates tested. Conclusion: the results from this review showed that garlic is an Anti-Candida herb. It showed that Fresh garlic extract possess a greater influence than garlic powder extract. The results of this study support the use of garlic in health products and herbal remedies. Meanwhile, more clinical trials should be conducted to support its anti-candidia effects.

[学科分类] 药理学

[关键词] Rasoul Rahimi;Allium Sativum;Phytochemicals;Therapeutic effects;Pharmacognosy;Alternative