In-vivo measurement of sound-induced motions in the gerbil cochlea

[摘要] (cont.) We identified the removal of the RWM as the cause for elevated CAP thresholds by comparing the CAP thresholds before and after removing the RWM to drop beads on the BM as essential reflective targets. Previous studies also suggest that large CAP threshold increases are common in the gerbil base ([10], [6]). Similar techniques have led to greater success in larger mammals; however, we hope to apply the lessons learned from measuring the in vivo gerbil cochlea to mice, the only species that would allow us to determine the micromechanical changes underlying genetic hearing disorders.

[发布机构] Massachusetts Institute of Technology