CARCINOEMBRYONIC ANTIGEN INHIBITS NEUTROPHIL ACTIVATION BY N-FORMYL-METHIONYL-LEUCYL-PHENYLALANINE -

[摘要] ABSTRACT: Carcinoembryonic antigen (CEA) is a surface glycoprotein expressed in human epithelial cells and is released from their surface, especially during colorectal cancer. Frequently, colorectal cancer is accompanied by inflammation, where tumor-infiltrating neutrophils play an important role. CEA was also found to be a strong chemotactic agent for neutrophils. The purpose of this study was to find out if CEA can enhance neutrophil priming and activation. Primed neutrophils were activated by.

[学科分类] 仪器