Hypertensive Cardiovascular and Renal Disease and Target Organ Damage: Lessons from Animal Models

[摘要] Abstract This brief review discusses some aspects of hypertensive damage to the kidneys and cardiovascular system. A comparison of renal and cardiac manifestations of hypertensive disease between results of clinical and experimental studies was made, with a major focus on the possible role of salt and the renin-angiotensin system (RAS) in inducing target organ damage. Thus, some degree of renal impairment is often present in patients with essential hypertension, varying from microalbuminuria to .

[学科分类] 心脏病和心血管学

[关键词] Arterial pressure;Cardiac/renal damage;Giraffe;Hypertension;Salt intake;SHR