Adjusting for Urinary Creatinine Overestimates Arsenic Concentrations in Diabetics

[摘要] Abstract Background/Aims: Arsenic (As) is linked to insulin resistance in animal studies, but the effect of low-level As exposure on the prevalence of diabetes in humans is uncertain. An optimal method to report inorganic As in humans has not been established. Measurements of As in spot urine are usually adjusted to creatinine (Cr). However, urinary Cr is an independent variable in diabetes. Our aims are to optimize reporting of urinary As in the setting of diabetes and insulin resistance. Metho.

[学科分类] 心脏病和心血管学

[关键词] Arsenic;Creatinine;Diabetes;Insulin resistance;Specific gravity