Magnetic resonance imaging of the cerebral metabolic rate of oxygen (CMRO₂)

[摘要] (cont.) QUIXOTIC-measured CMRO₂ is found to be within the expected physiological range and is comparable to values reported by other techniques. QUIXOTIC is then applied to evaluate CMRO₂ response to carbon-dioxide-induced hypercapnia in awake humans. In this study, CMRO₂ is observed to decrease in response to mild hypercapnia. Finally, pilot studies that show feasibility of QUIXOTIC-based functional MRI (fMRI) and so-called ;;turbo;; QUIXOTIC are presented and discussed.

[发布机构] Massachusetts Institute of Technology