The artificial pancreas, a challenge to research

[摘要] The first attempts for automated glucose control were made in the seventies of the last century. Nowadays several prototypes,for closed-loop glucose control are being tested, most of them in clinical research centers. Systems for automated glucose,control, also named 'artificial pancreas’ or 'closed-loop system’ consist of three parts; the first part concerns the input,or glucose measurement, the second part a mathematical model or control algorithm incorporated in a computer and the last,part the output, delivery of glucose regulatory hormones, insulin and sometimes glucagon. For ambulatory human use, the system,consists of subcutaneous continuous glucose monitor and subcutaneous administration of insulin and sometimes glucagon. In,this thesis it is demonstrated that:

[发布机构] University of Amterdam