Epistemology of Natural Strategies for Cardiac Tissue Repair

[摘要] Is there maintenance in complex biological systems or life is a continuous space-time drift? The emphasis that in the past years has been placed on tissue repair is, at least, misplaced since this property coincides with the same strategy that handles development and maintenance, a strategy that is broadly adaptive. It is not a mere philosophical question, since it deals with limited cellular resources; indeed, the evolution towards multicellularity is a form of adaptation to the environment that involves a high cost in terms of biological resources to handle differentiation, specialization, establishment of functional hierarchies, and development of a complex organisms. It is, therefore, evident that the availability of resources for other forms of adaptation in adult life, such as the re-generation process for maintenance or repair, is limited.

[学科分类] 心脏病和心血管学

[关键词] arrow of time;cardiovascular disease;cellular resources;entropy;environment;information;life;natural strategy;structuring of time