Erythrocyte Efferocytosis by the Arterial Wall Promotes Oxidation in Early-Stage Atheroma in Humans

[摘要] BackgroundSince red blood cells (RBCs) are the predominant cellular blood component interacting with the arterial wall, we explored the role of RBCs efferocytosis by vascular smooth muscle cells (vSMCs) in the initiation of human atheroma.

[学科分类] 心脏病和心血管学

[关键词] smooth muscle cells;oxidative stress;iron;fatty streaks;hemoglobin;translational studies;vascular biology;atherosclerosis