No Evidence of a Causal Relationship between Plasma Homocysteine and Type 2 Diabetes: A Mendelian Randomization Study

[摘要] Background: Several observational studies have shown an association between increased circulating homocysteine and risk of type 2 diabetes (T2D). We aimed to assess whether this relation is causal using genetic data from large populations of individuals of European descent.

[学科分类] 心脏病和心血管学

[关键词] homocysteine;type 2 diabetes;Mendelian randomization;MTHFR;association