Towards personalised medicine for cancer

[摘要] Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies,for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated,cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit,assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration,of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.,

[发布机构] University of Amterdam